Clinical Dermatology
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Clinical Dermatology
Skin disease in perspective
Skin disease in perspective Skin disease in perspective: Causes Skin disease in perspective: Prevalence Skin disease in perspective: ImpactThe function and structure of the skin
The function and structure of the skin Skin Epidermis The dermo-epidermal junction Skin Dermis The skin immune system Some cellular components of the skin immune system Molecular components of the skin immune system Hypersensitivity reactions in the skinDiagnosis of skin disorders
Diagnosis of skin disorders Diagnosis of skin disorders: Examination Special tools and techniques - Diagnosis of skin disorders Assessment - Diagnosis of skin disorders Side-room and office tests - Diagnosis of skin disorders Laboratory tests - Diagnosis of skin disorders Disorders of keratinization The ichthyoses - Disorders of keratinization Ichthyosis vulgaris X-linked recessive ichthyosis Collodion baby Lamellar ichthyosis and non-bullous ichthyosiform erythroderma Epidermolytic hyperkeratosis (bullous ichthyosiform erythroderma) Other ichthyosiform disorders Acquired ichthyosis Keratosis pilaris Keratosis follicularis (Darier’s disease) Keratoderma of the palms and soles Knuckle pads Callosities and cornsPsoriasis
Cause and pathogenesis of Psoriasis Psoriasis: Precipitating factors Psoriasis: Histology Psoriasis: Presentation Psoriasis: Complications Psoriasis: Differential diagnosis, Investigations Psoriasis: Treatment Psoriasis: Local treatments Psoriasis: Ultraviolet radiation treatments Psoriasis: Special situations treatments Psoriasis: Systemic treatment Psoriasis: Combination therapy treatmentOther papulosquamous disorders
Pityriasis rosea Lichen planus Pityriasis rubra pilaris Parapsoriasis and premycotic eruption Pityriasis lichenoides Erythroderma/exfoliative dermatitisEczema and dermatitis
Eczema and dermatitis: Terminology Classification of eczema Eczema and dermatitis: Pathogenesis Eczema and dermatitis: Histology Eczema and dermatitis: Clinical appearance Eczema and dermatitis: Complications, Differential diagnosis Eczema and dermatitis: Investigations Irritant contact dermatitis Allergic contact dermatitis Occupational dermatitis Atopic eczema Seborrhoeic eczema Discoid (nummular) eczema Pompholyx Gravitational (stasis) eczema Asteatotic eczema Localized neurodermatitis (lichen simplex) Juvenile plantar dermatosisReactive erythemas and vasculitis
Urticaria (hives, ‘nettle-rash’) Erythema multiforme Erythema nodosum Leucocytoclastic Polyarteritis nodosa Wegener’s granulomatosisBullous diseases
Bullous diseases Pemphigus Other causes of subcorneal and intraepidermal blistering Pemphigoid Pemphigoid gestationis (herpes gestationis) Cicatricial pemphigoid Linear IgA bullous disease Acquired epidermolysis bullosa Dermatitis herpetiformis Other causes of subepidermal blisters Toxic epidermal necrolysis (Lyell’s disease) Epidermolysis bullosaConnective tissue disorders
Connective tissue disorders Systemic lupus erythematosus Subacute cutaneous lupus erythematosus Discoid lupus erythematosus Dermatomyositis Systemic sclerosis CREST syndrome Eosinophilic fasciitis Morphoea Lichen sclerosus Mixed connective tissue disease Other connective tissue diseasesDisorders of blood vessels and lymphatics
Disorders involving small blood vessels Arterial disease Deep vein thrombosis - Venous disease Thrombophlebitis - Venous disease Venous hypertension, the gravitational syndrome and venous leg ulceration Purpura - Venous disease Disorders of the lymphaticsSebaceous and sweat gland disorders
Sebaceous glands Acne Acne Treatment Rosacea Eccrine sweat glands Apocrine sweat glandsRegional dermatology
The hair The hair: Classification The hair cycle Alopecia Alopecia areata Androgenetic alopecia (male-pattern baldness) Traction alopecia Patchy hair loss caused by skin disease Diffuse hair loss Rare genetic causes of hypotrichosis Hirsutism and hypertrichosis Hypertrichosis The nails The nails: Effects of trauma The nail in systemic disease Nail changes in the common dermatoses The nails Infections Some other nail abnormalities The mouth and genitals Lichen planus Candidiasis Contact stomatitis Bullous diseases Aphthae Some other oral lumps, bumps and colour changes Squamous cell carcinoma Vulvovaginitis Lichen sclerosus Vulval and scrotal pruritus Malignant conditions: Squamous cell carcinomaInfections
Bacterial infections: The resident flora of the skin Streptococcal infections Spirochaetal infections Other Bacterial infections Mycobacterial infections Other mycobacterial infections Viral infections: Viral warts Viral infections: Varicella (chickenpox) Viral infections: Herpes zoster Molluscum contagiosum Orf Acquired immunodeficiency syndrome (AIDS) Mucocutaneous lymph node syndrome (Kawasaki’s disease) Gianotti–Crosti syndrome Herpangina, Measles, Rubella, Erythema infectiosum Dermatophyte infections (ringworm) - Fungal infections Candidiasis - Fungal infections Pityriasis versicolor Deep fungal infectionsInfestations
Insect bites - Arthropods Papular urticaria Bed bugs (Hemiptera) and Myiasis Lice infestations (pediculosis) Scabies Infestations of Parasitic wormsSkin reactions to light
Skin reactions to light Sunburn Phototoxicity Photoallergy Chronic actinic dermatitis (actinic reticuloid) Polymorphic light eruption Actinic prurigo Solar urticaria Lupus erythematosus Cutaneous ageingDisorders of pigmentation
Normal skin colour Abnormal skin colours Decreased melanin pigmentation Disorders with increased pigmentation (hypermelanosis)Skin tumours
Skin tumours: Prevention Benign Premalignant tumours Basal cell carcinoma (rodent ulcer) Squamous cell carcinoma Malignant melanoma Paget’s disease of the nipple Tumours of the dermis: Benign Tumours of the dermis: Malformations Tumours of the dermis: Haemangiomas Tumours of the dermis: Lymphangiomas Other benign dermal tumours Malignant: Kaposi’s sarcoma Lymphomas and leukaemias Dermatofibrosarcoma protuberans and Cutaneous metastasesThe skin in systemic disease
The skin and internal malignancy The skin and diabetes mellitus The skin in sarcoidosis The skin in liver disease The skin in renal disease The porphyrias Some metabolic disorders Generalized pruritus Pyoderma gangrenosum The skin changes of pregnancyThe skin and the psyche
The skin and the psyche Reactions to skin disease Dermatoses precipitated or perpetuated by emotional factorsOther genetic disorders
Other genetic disorders Non-Mendelian genetics Neurofibromatosis Tuberous sclerosis Xeroderma pigmentosum Incontinentia pigmenti Ehlers–Danlos syndrome Pseudoxanthoma elasticumDrug eruptions
Drug eruptions Mechanisms Drug eruptions Presentation: Some drugs and the reactions they can cause Some common reaction patterns and drugs which can cause them Drug eruptions Course and Differential diagnosis Drug eruptions TreatmentMedical treatment
Medical treatment Therapeutic options Topical treatment Systemic therapyPhysical forms of treatment
Surgery - Physical forms of treatment Cryotherapy - Physical forms of treatment Radiotherapy - Physical forms of treatment Phototherapy - Physical forms of treatment Laser therapy - Physical forms of treatment
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