Combination therapy
If
psoriasis is resistant to one treatment, a combina-tion of treatments used
together may be the answer. Combination treatments can even prevent
side-effects by allowing less of each drug to be used. Common combinations
include topical vitamin D analogues with either local steroids or UVB,
dithranol following a tar bath and UVB (Ingram regimen) and coal tar fol-lowing
a tar bath and UVB (Goeckerman regimen).
Rotational
therapy may also minimize the toxicity of some treatmentsaan example would be
PUVA, metho-trexate, acitretin and cyclosporin, each used separately for 1–2
years before moving on to the next treatment.
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