cardinal feature of these conditions is inflamma-tion in the connective tissue
which leads to dermal atrophy or sclerosis, to arthritis, and sometimes to
abnormalities in other organs. In addition, antibodies form against normal
tissues and cellular components; these disorders are therefore classed as
autoimmune. Many have difficulty in remembering which antibody features in
which condition: Table 10.1 should help here.
main connective tissue disorders present as a spectrum ranging from the benign
cutaneous variants to severe multisystem diseases (Table 10.2).