Essential Clinical Immunology

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Essential Clinical Immunology

Basic Components of the Immune System


=> Basic Components of the Immune System
=> Antigens
=> Antibody
=> T Cells and their Receptors
=> Major Histocompatibility Complex
=> Adhesion Molecules
=> Cytokines
=> Initiation of the Immune Response
=> Antibody Production
=> Functional Components of the Immune System
=> Tissue Damage Pathways: Hypersensitivity Reactions

Immunological Techniques


=> Antibody Production
=> Immunological Assays
=> Lymphocytic Assays
=> Fluorescein-Activated Cell Sorter
=> Lymphocyte Proliferation Assays
=> DNA Technology Assays

Immune Regulation


=> Immuno suppression: Immunosuppressive Drugs
=> Antibodies and Other Immunosuppressive Methods
=> Immunopotentiation
=> Cytokine Immunomodulation
=> Cellular Vaccines and Modulations There of Dendritic Cell Vaccines

Immunological Aspects of Infection


=> Non Specific Resistance - Immunological Aspects of Infection
=> Adaptive Immunity
=> Bacterial Infection
=> Bacterial Superantigens
=> Bacterial Evasion of Immune Defense
=> Viral Infections
=> Fungal Infection
=> Parasitic Infection

Immunological Aspects of Immunodeficiency Diseases


=> Immunological Aspects of Immunodeficiency Diseases
=> Defects in Anatomical or Physiological Barriers to Infection
=> Disorders Characterized By Antibody Deficiency
=> Clinical Manifestations of Antibody Deficiency
=> Major Categories of Antibody Deficiency
=> Defects in Cell-Mediated Immunity (T-Cell Dependent Immunity)
=> Manifestations of T-Cell Deficiency
=> Major Categories of Combined Immunodeficiency
=> Immunological and Molecular Classification of SCID
=> Treatment of SCID
=> DiGeorge’s Syndrome (Thymic Aplasia)
=> Phagocyte Deficiencies
=> Neutropenia - Phagocyte Deficiencies
=> Defects in Leucocyte Migration - Phagocyte Deficiencies
=> Defects in Bacterial Killing - Phagocyte Deficiencies
=> Defects in Killing of Intracellular Bacteria by Activated Macrophages
=> Complex Immunodeficiencies Due to Miscellaneous Defects
=> Immunodeficiencies Resulting in Defective Homeostasis of the Immune System
=> Defects in the Cytolytic Pathway
=> Inherited Deficiency of the Complement System
=> Defects in Innate Immunity

Autoimmunity


=> Definitions and Types of Autoimmunity
=> Type II Autoimmune Reactions - Mechanisms of Autoimmune Tissue Injury and Examples
=> Type IIA Autoimmune Reaction: Autoimmune Hemolytic Anemia - Mechanisms of Autoimmune Tissue Injury and Examples
=> Type IIB Hypersensitivity: Graves’ Disease - Mechanisms of Autoimmune Tissue Injury and Examples
=> Type IIB Hypersensitivity: Myasthenia Gravis - Mechanisms of Autoimmune Tissue Injury and Examples
=> Type III Autoimmune Reactions (Immune Complex Disease) - Mechanisms of Autoimmune Tissue Injury
=> Type IV Autoimmune Reactions (T-Cell Mediated) - Mechanisms of Autoimmune Tissue Injury and Examples
=> Epidemiology of Autoimmune Disease
=> Animal Models of Autoimmune Disease
=> SLE (NZB X NZW F1, MRL, BXSB, TMPD)
=> Rheumatoid Arthritis (Collagen-Induced Arthritis, TTP Deficiency, K/BxN Model)
=> Multiple Sclerosis (Experimental Autoimmune Encephalomyelitis)
=> Type I Diabetes (Nonobese Diabetic Mouse Model)
=> Autoimmune Thyroiditis (Experimental Autoimmune Thyroiditis)
=> Pathogenesis of Autoimmune Disease
=> Treatment of Autoimmune Disease

Chronic Lymphocytic Leukemia


=> B-Cell Activation and Maturation
=> Characterizing the Heterogeneity of B-CLL by Molecular and Clinical Subtypes
=> Development of B-CLL From Normal B Lymphocytes
=> Correlations Between the Cellular and Molecular Features of the Disease With the Clinical Course of B-CLL
=> Summary Remarks on the Development, Growth, and Evolution of B-CLL
=> Animal Models of B-CLL
=> Clinical Implications and the Development of Novel Therapeutics

Immunology of HIV Infections


=> Immunological and Biological Parameters of Disease
=> Animal Models of HIV Infection
=> Vaccines to Prevent HIV Infection
=> Vaccine Candidates - Immunology of HIV Infections

Immunological Aspects of Allergy and Anaphylaxis


=> Immunological Aspects of Allergy and Anaphylaxis
=> Allergic Hypersensitivity
=> Atopy
=> Systemic Anaphylaxis and Anaphylactoid Reactions
=> Allergic Conjunctivitis
=> Allergic Disease of the Respiratory Tract
=> Allergic Rhinitis: Overview, Clinical Disease States, Experimental Models
=> Allergic Asthma: Overview, Immunology, Experimental Models
=> Food Allergy and Intolerance: Diagnosis, Food Intolerance
=> Skin Diseases and Allergy

Immunological Aspects of Skin Diseases


=> Immunological Aspects of Skin Diseases
=> Psoriasis - Skin Diseases
=> Alopecia Areata
=> Antibody Induced Bullous Skin Lesions

Experimental Approaches to the Study of Autoimmune Rheumatic Diseases


=> Experimental Approaches to the Study of Autoimmune Rheumatic Diseases
=> Types of Animal Models
=> Rheumatoid Arthritis: Etiology, Pathogenesis, Clinical Features, Treatment
=> Animal Models of Rheumatoid Arthritis
=> Systemic Lupus Erythematosus: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment
=> Animal Models of Systemic Lupus Erythematosus(SLE)
=> Sjogren’s Syndrome: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models
=> Progressive Systemic Sclerosis: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models
=> Polymyositis: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models
=> Seronegative Spondyloarthropathy: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models

Immunological Aspects of Cardiac Disease


=> Rheumatic Fever
=> Epidemiology and Pathogenesis of Rheumatic Fever
=> Rheumatic Fever: Genetics
=> Etiologic Considerations of Rheumatic Fever
=> Animal Models of Rheumatic Fever
=> Streptococcal Vaccine Candidate
=> Chagas’ Disease
=> Host-Parasite Interaction and Host Susceptibility of Chagas’ Disease
=> Pathogenesis and Modulation of Immune Function - Chagas’ Disease
=> Autoimmunity and Pathogenesis of Chagas’ Disease
=> Molecular Mimicry in Chagas’ Disease
=> Parasite-Directed Pathogenesis of Chagas’ Disease
=> Myocarditis - Immune-Mediated Myocardial Diseases
=> Dilated Cardiomyopathy - Immune Mediated Myocardial Diseases

Immunological Aspects of Chest Diseases


=> Immunological Aspects of Chest Diseases: The Case of Tuberculosis
=> Epidemiology - Tuberculosis
=> TB and AIDS
=> Clinical Tuberculosis
=> Experimental Studies of Tuberculosis
=> The Mouse Model of Chronic Tuberculosis
=> Host-Pathogen Interactions in TB

Immunological Aspects of Gastrointestinal and Liver Disease


=> Mucosal Immunity
=> Pernicious Anemia - Immune Mediated Diseases of the Gastrointestinal Tract
=> Gluten Sensitive Enteropathy - Immune Mediated Diseases of the Gastrointestinal Tract
=> Inflammatory Bowel Disease - Immune Mediated Diseases of the Gastrointestinal Tract
=> Liver Immunology
=> Hepatitis B - Diseases of the Liver
=> Hepatitis C - Diseases of the Liver
=> Other Hepatitis Viruses - Diseases of the Liver
=> Primary Biliary Cirrhosis - Diseases of the Liver
=> Primary Sclerosing Cholangitis - Diseases of the Liver
=> Autoimmune Hepatitis - Diseases of the Liver

Immunological Aspects of Endocrine Disease


=> Insulin-Dependent Diabetes Mellitus
=> Animal Models of Insulin-Dependent Diabetes Mellitus
=> Β-Cell Lesion: Nature of Effector Cells - Insulin Dependent Diabetes Mellitus
=> Rupture of Tolerance to Β-Cell Antigens - Insulin Dependent Diabetes Mellitus
=> Etiology of Insulin Dependent Diabetes Mellitus
=> Clinical Considerations of Insulin Dependent Diabetes Mellitus

Immune Mediated Neurological Syndromes


=> Multiple Sclerosis
=> Guillain-Barré Syndrome
=> Myasthenia Gravis
=> Central Nervous System Systemic Lupus Erythematosus
=> Animal Models of Central Nervous System

Immunological Aspects of Renal Disease


=> Immunological Aspects of Renal Disease
=> Mechanisms of Immune Injury to the Kidneys
=> Specific Immune-Related Renal Diseases: IgA Nephropathy
=> Minimal Change Disease
=> Focal Sclerosing Glomerulosclerosis
=> Membranous Nephropathy
=> Membranoproliferative Glomerulonephritis
=> Rapidly Progressive Glomerulonephritis
=> Lupus Nephritis
=> Acute Poststreptococcal Glomerulonephritis
=> Mixed Cryoglobulinemia

Immunological Aspects of Transplantation


=> Immunological Aspects of Transplantation
=> Immunological Considerations of Transplantation
=> Laboratory Testing for Compatibility in Transplantation
=> Types of Solid Organ Allograft Rejection
=> Prevention and Management of Solid Organ Allograft Rejection
=> Solid Organ Transplantation Outcomes
=> Hematopoietic Stem Cell Transplantation



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