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Essential Clinical Immunology -

Essential Clinical Immunology

Basic Components of the Immune System


-:- Basic Components of the Immune System
-:- Antigens
-:- Antibody
-:- T Cells and their Receptors
-:- Major Histocompatibility Complex
-:- Adhesion Molecules
-:- Cytokines
-:- Initiation of the Immune Response
-:- Antibody Production
-:- Functional Components of the Immune System
-:- Tissue Damage Pathways: Hypersensitivity Reactions

Immunological Techniques


-:- Antibody Production
-:- Immunological Assays
-:- Lymphocytic Assays
-:- Fluorescein-Activated Cell Sorter
-:- Lymphocyte Proliferation Assays
-:- DNA Technology Assays

Immune Regulation


-:- Immuno suppression: Immunosuppressive Drugs
-:- Antibodies and Other Immunosuppressive Methods
-:- Immunopotentiation
-:- Cytokine Immunomodulation
-:- Cellular Vaccines and Modulations There of Dendritic Cell Vaccines

Immunological Aspects of Infection


-:- Non Specific Resistance - Immunological Aspects of Infection
-:- Adaptive Immunity
-:- Bacterial Infection
-:- Bacterial Superantigens
-:- Bacterial Evasion of Immune Defense
-:- Viral Infections
-:- Fungal Infection
-:- Parasitic Infection

Immunological Aspects of Immunodeficiency Diseases


-:- Immunological Aspects of Immunodeficiency Diseases
-:- Defects in Anatomical or Physiological Barriers to Infection
-:- Disorders Characterized By Antibody Deficiency
-:- Clinical Manifestations of Antibody Deficiency
-:- Major Categories of Antibody Deficiency
-:- Defects in Cell-Mediated Immunity (T-Cell Dependent Immunity)
-:- Manifestations of T-Cell Deficiency
-:- Major Categories of Combined Immunodeficiency
-:- Immunological and Molecular Classification of SCID
-:- Treatment of SCID
-:- DiGeorge’s Syndrome (Thymic Aplasia)
-:- Phagocyte Deficiencies
-:- Neutropenia - Phagocyte Deficiencies
-:- Defects in Leucocyte Migration - Phagocyte Deficiencies
-:- Defects in Bacterial Killing - Phagocyte Deficiencies
-:- Defects in Killing of Intracellular Bacteria by Activated Macrophages
-:- Complex Immunodeficiencies Due to Miscellaneous Defects
-:- Immunodeficiencies Resulting in Defective Homeostasis of the Immune System
-:- Defects in the Cytolytic Pathway
-:- Inherited Deficiency of the Complement System
-:- Defects in Innate Immunity

Autoimmunity


-:- Definitions and Types of Autoimmunity
-:- Type II Autoimmune Reactions - Mechanisms of Autoimmune Tissue Injury and Examples
-:- Type IIA Autoimmune Reaction: Autoimmune Hemolytic Anemia - Mechanisms of Autoimmune Tissue Injury and Examples
-:- Type IIB Hypersensitivity: Graves’ Disease - Mechanisms of Autoimmune Tissue Injury and Examples
-:- Type IIB Hypersensitivity: Myasthenia Gravis - Mechanisms of Autoimmune Tissue Injury and Examples
-:- Type III Autoimmune Reactions (Immune Complex Disease) - Mechanisms of Autoimmune Tissue Injury
-:- Type IV Autoimmune Reactions (T-Cell Mediated) - Mechanisms of Autoimmune Tissue Injury and Examples
-:- Epidemiology of Autoimmune Disease
-:- Animal Models of Autoimmune Disease
-:- SLE (NZB X NZW F1, MRL, BXSB, TMPD)
-:- Rheumatoid Arthritis (Collagen-Induced Arthritis, TTP Deficiency, K/BxN Model)
-:- Multiple Sclerosis (Experimental Autoimmune Encephalomyelitis)
-:- Type I Diabetes (Nonobese Diabetic Mouse Model)
-:- Autoimmune Thyroiditis (Experimental Autoimmune Thyroiditis)
-:- Pathogenesis of Autoimmune Disease
-:- Treatment of Autoimmune Disease

Chronic Lymphocytic Leukemia


-:- B-Cell Activation and Maturation
-:- Characterizing the Heterogeneity of B-CLL by Molecular and Clinical Subtypes
-:- Development of B-CLL From Normal B Lymphocytes
-:- Correlations Between the Cellular and Molecular Features of the Disease With the Clinical Course of B-CLL
-:- Summary Remarks on the Development, Growth, and Evolution of B-CLL
-:- Animal Models of B-CLL
-:- Clinical Implications and the Development of Novel Therapeutics

Immunology of HIV Infections


-:- Immunological and Biological Parameters of Disease
-:- Animal Models of HIV Infection
-:- Vaccines to Prevent HIV Infection
-:- Vaccine Candidates - Immunology of HIV Infections

Immunological Aspects of Allergy and Anaphylaxis


-:- Immunological Aspects of Allergy and Anaphylaxis
-:- Allergic Hypersensitivity
-:- Atopy
-:- Systemic Anaphylaxis and Anaphylactoid Reactions
-:- Allergic Conjunctivitis
-:- Allergic Disease of the Respiratory Tract
-:- Allergic Rhinitis: Overview, Clinical Disease States, Experimental Models
-:- Allergic Asthma: Overview, Immunology, Experimental Models
-:- Food Allergy and Intolerance: Diagnosis, Food Intolerance
-:- Skin Diseases and Allergy

Immunological Aspects of Skin Diseases


-:- Immunological Aspects of Skin Diseases
-:- Psoriasis - Skin Diseases
-:- Alopecia Areata
-:- Antibody Induced Bullous Skin Lesions

Experimental Approaches to the Study of Autoimmune Rheumatic Diseases


-:- Experimental Approaches to the Study of Autoimmune Rheumatic Diseases
-:- Types of Animal Models
-:- Rheumatoid Arthritis: Etiology, Pathogenesis, Clinical Features, Treatment
-:- Animal Models of Rheumatoid Arthritis
-:- Systemic Lupus Erythematosus: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment
-:- Animal Models of Systemic Lupus Erythematosus(SLE)
-:- Sjogren’s Syndrome: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models
-:- Progressive Systemic Sclerosis: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models
-:- Polymyositis: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models
-:- Seronegative Spondyloarthropathy: Epidemiology, Etiology, Pathogenesis, Clinical Features, Treatment, Animal Models

Immunological Aspects of Cardiac Disease


-:- Rheumatic Fever
-:- Epidemiology and Pathogenesis of Rheumatic Fever
-:- Rheumatic Fever: Genetics
-:- Etiologic Considerations of Rheumatic Fever
-:- Animal Models of Rheumatic Fever
-:- Streptococcal Vaccine Candidate
-:- Chagas’ Disease
-:- Host-Parasite Interaction and Host Susceptibility of Chagas’ Disease
-:- Pathogenesis and Modulation of Immune Function - Chagas’ Disease
-:- Autoimmunity and Pathogenesis of Chagas’ Disease
-:- Molecular Mimicry in Chagas’ Disease
-:- Parasite-Directed Pathogenesis of Chagas’ Disease
-:- Myocarditis - Immune-Mediated Myocardial Diseases
-:- Dilated Cardiomyopathy - Immune Mediated Myocardial Diseases

Immunological Aspects of Chest Diseases


-:- Immunological Aspects of Chest Diseases: The Case of Tuberculosis
-:- Epidemiology - Tuberculosis
-:- TB and AIDS
-:- Clinical Tuberculosis
-:- Experimental Studies of Tuberculosis
-:- The Mouse Model of Chronic Tuberculosis
-:- Host-Pathogen Interactions in TB

Immunological Aspects of Gastrointestinal and Liver Disease


-:- Mucosal Immunity
-:- Pernicious Anemia - Immune Mediated Diseases of the Gastrointestinal Tract
-:- Gluten Sensitive Enteropathy - Immune Mediated Diseases of the Gastrointestinal Tract
-:- Inflammatory Bowel Disease - Immune Mediated Diseases of the Gastrointestinal Tract
-:- Liver Immunology
-:- Hepatitis B - Diseases of the Liver
-:- Hepatitis C - Diseases of the Liver
-:- Other Hepatitis Viruses - Diseases of the Liver
-:- Primary Biliary Cirrhosis - Diseases of the Liver
-:- Primary Sclerosing Cholangitis - Diseases of the Liver
-:- Autoimmune Hepatitis - Diseases of the Liver

Immunological Aspects of Endocrine Disease


-:- Insulin-Dependent Diabetes Mellitus
-:- Animal Models of Insulin-Dependent Diabetes Mellitus
-:- Β-Cell Lesion: Nature of Effector Cells - Insulin Dependent Diabetes Mellitus
-:- Rupture of Tolerance to Β-Cell Antigens - Insulin Dependent Diabetes Mellitus
-:- Etiology of Insulin Dependent Diabetes Mellitus
-:- Clinical Considerations of Insulin Dependent Diabetes Mellitus

Immune Mediated Neurological Syndromes


-:- Multiple Sclerosis
-:- Guillain-Barré Syndrome
-:- Myasthenia Gravis
-:- Central Nervous System Systemic Lupus Erythematosus
-:- Animal Models of Central Nervous System

Immunological Aspects of Renal Disease


-:- Immunological Aspects of Renal Disease
-:- Mechanisms of Immune Injury to the Kidneys
-:- Specific Immune-Related Renal Diseases: IgA Nephropathy
-:- Minimal Change Disease
-:- Focal Sclerosing Glomerulosclerosis
-:- Membranous Nephropathy
-:- Membranoproliferative Glomerulonephritis
-:- Rapidly Progressive Glomerulonephritis
-:- Lupus Nephritis
-:- Acute Poststreptococcal Glomerulonephritis
-:- Mixed Cryoglobulinemia

Immunological Aspects of Transplantation


-:- Immunological Aspects of Transplantation
-:- Immunological Considerations of Transplantation
-:- Laboratory Testing for Compatibility in Transplantation
-:- Types of Solid Organ Allograft Rejection
-:- Prevention and Management of Solid Organ Allograft Rejection
-:- Solid Organ Transplantation Outcomes
-:- Hematopoietic Stem Cell Transplantation