PROTEIN
S DEFICIENCY
Protein
S is another natural anticoagulant normally produced in the liver. APC requires
Protein S to inactivate certain clotting fac-tors. When the level of Protein S
is deficient, this inactivation process is diminished, and the risk for
thrombosis can be increased. Like patients with Protein C deficiency, those with
Protein S defi-ciency have a greater risk for recurrent venous thrombosis at a
young age, as young as 15 years.
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