Seminal Plasma Protein Allergy - Vulvovaginal Infections

SEMINAL PLASMA PROTEIN ALLERGY

Women with this condition develop an immunologic response to human semen, resulting in vaginal inflammation. Symptoms vary from local inflammation and pruritus to rare systemic anaphy-laxis after exposure. Diagnosis is usually based on the absence of symptoms with condom use. Treatment may include cromolyn vaginal cream and immunotherapy. The success rate of treatment varies, and referral to an immunologist may be warranted.