PREGNANCY-RELATED
NEOPLASM
Hydatidiform mole is a type of gestational trophoblastic
neo-plasm that occurs in 1 in 1,000 pregnancies. Delayed menses with spotting
is the most common sign. Hyperemesis and uterine en-largement beyond that
expected for gestational dates are also indicative. Moles can be partial or
complete. Complete moles are more likely to be associated with medical
complications. Pregnancy-induced hypertension (formerly called preeclampsia),
pregnancy-related complex of symptoms that may include edema, hypertension, and
proteinuria, may occur. Treatment con-sists of suction curettage followed by
monitoring serial beta-human chorionic gonadotropin (HCG) levels, which usually
take about 2.5 months to return to normal. This condition may recur. Moles can
be invasive also.
Choriocarcinoma, another gestational neoplasm that
usuallyoccurs in the postpartum period, is a placental site trophoblastic
tumor. These malignancies are being diagnosed more readily and treated more
effectively today due to the availability of testing for HCG, a sensitive
marker that can be used for monitoring. Ultra-sound is also used for making the
diagnosis. These malignancies are usually found in obstetric patients and are
described in detail in obstetric and oncologic textbooks. Nurses need to be
aware that these conditions are traumatic, anxiety-producing, and often very
stressful for the patient since they are often associated with pregnancy loss.
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