Drugs Used in Partial Seizures Generalized Tonic-Clonic Seizures

DRUGS USED IN PARTIAL SEIZURES GENERALIZED TONIC-CLONIC SEIZURES

The classic major drugs for partial and generalized tonic-clonic seizures are phenytoin (and congeners), carbamazepine, valproate, and the barbiturates. However, the availability of newer drugs— eslicarbazepine, lamotrigine, levetiracetam, gabapentin, oxcarba-zepine, pregabalin, retigabine, topiramate, vigabatrin, lacosamide, and zonisamide—is altering clinical practice in countries where these compounds are available.