Definition, Types, Causes, Signs and Symptoms, Diagnosis, management, Complications - Fibrosis | 12th Nursing : Chapter 2 : Medical Surgical and Applied Nursing Management Psychology of Human Diseases

Chapter: 12th Nursing : Chapter 2 : Medical Surgical and Applied Nursing Management Psychology of Human Diseases

Fibrosis

Pathological accumulation of extracellular matrix (ECM) proteins resulting in fibrosis or scarring and thickening of the affected tissue.

Fibrosis

Fibrosis, or scarring, is a condition where the wound healing is exaggerated. It is progressive in nature eventually leading to organ malfunction and death. Fibrosis affects nearly every tissue in the body. The growth of new capillaries into the inert material (exudates or thrombus), the migration of macrophages and the proliferation of fibroblasts resulting in fibrosis.

 

Definition

Pathological accumulation of extracellular matrix (ECM) proteins resulting in fibrosis or scarring and thickening of the affected tissue.

 

Causes

               Unknown

               Radiation

               Cigarette smoke

               Chemicals

               Chronic alcoholism

               Occupational hazards (silicosis, asbestosis)

               Chronic infection

               Fatty liver disease

               Hepatitis B or hepatitis C.

 

Types

               Lung fibrosis or pulmonary fibrosis - occurs as a result of long standing infections such as tuberculosis or pneumonia.

               Cirrhosis of liver refers to the scar tissue and nodules that replace liver tissue that disrupt liver function.

               Heart fibrosis - areas of the heart that have become damaged due to myocardial infarction.

               Mediastinal fibrosis - calcified fibrosis of the lymph nodes, which can block respiratory channels and blood vessels.

               Retroperitoneal cavity fibrosis - fibrosis of the soft tissue in the retro-peritoneum

               Myelofibrosis - scarring of the bone marrow that prevents the normal production of blood cells.

               Keloid-fibrosis on the skin in response to injury

               Scleroderma or systemic sclerosis - an autoimmune disease of the connective tissue that primarily affects the skin but can also involve other organs such as the kidneys, heart and lungs.

 

Diagnosis

               Tissue biopsy


Management

Stem Cell therapy

 

Complication

               Joints - stiffness and pain

               Tendons – contracture, deformity

               Shoulder capsule - adhesive capsulitis and frozen shoulder

               Fibrosis of the soft tissue in the penis

 

Tags : Definition, Types, Causes, Signs and Symptoms, Diagnosis, management, Complications , 12th Nursing : Chapter 2 : Medical Surgical and Applied Nursing Management Psychology of Human Diseases
Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail
12th Nursing : Chapter 2 : Medical Surgical and Applied Nursing Management Psychology of Human Diseases : Fibrosis | Definition, Types, Causes, Signs and Symptoms, Diagnosis, management, Complications

Related Topics

12th Nursing : Chapter 2 : Medical Surgical and Applied Nursing Management Psychology of Human Diseases


Privacy Policy, Terms and Conditions, DMCA Policy and Compliant

Copyright © 2018-2023 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.