Diagnostic
& Therapeutic Blocks
Local anesthetic nerve blocks are useful in
delineat-ing pain mechanisms, and they play a major role in the management of
patients with acute or chronic pain. Pain relief following diagnostic nerve
blockade often carries favorable prognostic implications for a subsequent
therapeutic series of blocks. Although the utility of differential nerve blocks
in distinguish-ing between somatic and sympathetic mechanisms has been
questioned, this technique can identify patients exhibiting a placebo response
and those with psychogenic mechanisms. In selected patients, “per-manent”
neurolytic nerve blocks may be appropriate.
The efficacy of nerve blocks is presumably
due to interruption of afferent nociceptive activity. This is in addition to,
or in combination with, blockade of afferent and efferent limbs of abnormal
reflex activ-ity involving sympathetic nerve fibers and skeletal muscle
innervation. The pain relief frequently out-lasts (by hours up to several
weeks) the known pharmacological duration of the agent employed. Selection of
the type of block depends on the loca-tion of pain, its presumed mechanism, and
the skills of the treating physician. Local anesthetic solutions may be applied
locally (infiltration), or at a specific peripheral nerve, somatic plexus, sympathetic
gan-glia, or nerve root. The local anesthetic may also be applied centrally in
the neuraxis.
The use of ultrasound in interventional pain
medi-cine has increased over the past decade due to its utility in visualizing
vascular, neural, and other ana-tomic structures; its role as an alternative to
the use of fluoroscopy and iodine-based contrast agents; and progressive
improvements in technology lead-ing to better visual images and greater
simplicity of use. Most notably, ultrasound has become very useful for
visualizing blood vessels and potentially decreasing the incidence of
intravascular injection of particulate steroid medications. It may also be
helpful in decreasing the risk of pneumothorax and of intraperitoneal
injection. Procedures that may benefit from ultrasound guidance include trigger
point injections, nerve blocks, and joint injections.
Fluoroscopy is frequently used for
interventional pain procedures. It is highly effective for visualizing bony
structures and observing the spread of radiopaque contrast agents. Live
fluoroscopy with contrast agent should be used to minimize the risk of
intravascular injection of therapeutic agents. Care should be taken to avoid
excessive use of fluoroscopy and to employ appropriate radiation shielding,
given the risks of ionizing radiation to the patient and to the health care
team members in the fluoroscopy suite.
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