Myasthenia Gravis

Myasthenia Gravis

·        Antibodies to Ach receptors ® weakness, fatigues with repetition

·        Affects eye movement in 15%

·        Treatment:

o   Immunosuppressives: Prednisone, azathioprine, cyclosporin

o   Take out thymus – many have hyperplasia or thymoma

·        Myasthenia Gravis Crisis:

o   Triggers: Respiratory infection, change in medication

o   ® Respiratory failure due to weakness, can be insidious

o   Consider ICU admission and ventilation