Chapter: Clinical Anesthesiology: Perioperative & Critical Care Medicine: Acid-Base Management

Anesthetic Considerations in Patients With Alkalemia

Respiratory alkalosis seems to prolong the duration of opioid-induced respiratory depression; this effect may result from increased protein binding of opioids.

ANESTHETIC CONSIDERATIONS IN PATIENTS WITH ALKALEMIA

Respiratory alkalosis seems to prolong the duration of opioid-induced respiratory depression; this effect may result from increased protein binding of opi-oids. Cerebral ischemia can occur from marked reduction in cerebral blood flow during respiratory 10 alkalosis, particularly during hypotension.

The combination of alkalemia and hypokale-mia can precipitate severe atrial and ventricular arrhythmias. Potentiation of nondepolarizing neu-romuscular blockade is reported with alkalemia, but may be more directly related to concomitant hypokalemia.

Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail

Clinical Anesthesiology: Perioperative & Critical Care Medicine: Acid-Base Management : Anesthetic Considerations in Patients With Alkalemia |