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Chapter: Basic & Clinical Pharmacology : Histamine, Serotonin, & the Ergot Alkaloids

Histamine Receptor Antagonists

Compounds that competitively block histamine or act as inverse agonists at H1 receptors.

HISTAMINE RECEPTOR ANTAGONISTS

H1-RECEPTOR ANTAGONISTS

Compounds that competitively block histamine or act as inverse agonists at H1 receptors have been used in the treatment of allergic conditions for many years, and in the discussion that follows are referred to as antagonists. Many H1 antagonists are currently mar-keted in the USA. A large number are available without prescrip-tion, both alone and in combination formulations such as “cold pills” and “sleep aids” .

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Basic & Clinical Pharmacology : Histamine, Serotonin, & the Ergot Alkaloids : Histamine Receptor Antagonists |


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