Chapter: Basic & Clinical Pharmacology : Pharmacologic Management of Parkinsonism & Other Movement Disorders

Neuroprotective Therapy - Parkinsonism

The role of these agents remains to be established, however, and their use for therapeutic purposes is not indicated at this time.

NEUROPROTECTIVE THERAPY

Among the compounds under investigation as potential neuro-protective agents that may slow disease progression are antioxidants, antiapoptotic agents, glutamate antagonists, intraparenchymally administered glial-derived neurotrophic factor, coenzyme Q10, creatine, and anti-inflammatory drugs. The role of these agents remains to be established, however, and their use for therapeutic purposes is not indicated at this time. The possibility that rasagiline has a protective effect was discussed earlier.

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Basic & Clinical Pharmacology : Pharmacologic Management of Parkinsonism & Other Movement Disorders : Neuroprotective Therapy - Parkinsonism |