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These are the types of antigen–antibody reactions that are visualized directly by electron microscope. These are of the following types:
This is a test used to detect rotavirus and hepatitis A virus directly in feces. In this test, viral particles are mixed with spe-cific antisera and are demonstrated as clumps of virion particles under the electron microscope.
This test is used to detect antigen directly in tissue specimens, in which tissue sections are treated with peroxidase-labeled antisera to detect corresponding antigen. The peroxidase bound to the antigen is visualized under the electron microscope.
Electron-dense substances, such as ferritin are conjugated with antibody and such labeled antibodies reacting with antigen can be visualized under the electron microscope.
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