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Chapter: Medicine and surgery: Haematology and clinical Immunology

Hereditary haemorrhagic telangiectasia - Vascular causes of bleeding

Rare autosomal dominant vascular disorder resulting in telangiectasia and recurrent bleeding.

Vascular causes of bleeding

 


Hereditary haemorrhagic telangiectasia

 

Definition

 

Rare autosomal dominant vascular disorder resulting in telangiectasia and recurrent bleeding.


Clinical features

 

Dilation of small arteries and capillaries result in characteristic small red spots that blanch on pressure (telangiectasia) in the skin and mucous membranes particularly the nose and gastrointestinal tract. Patients suffer from recurrent epistaxis and chronic gastrointestinal bleeds.

 

Complications

Patients are prone to chronic iron deficiency anaemia.

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