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Chapter: Medical Physiology: Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth

Dental Abnormalities

The two most common dental abnormalities are caries and malocclusion.

Dental Abnormalities

The two most common dental abnormalities are caries and malocclusion. Caries refers to erosion of the teeth, whereas malocclusion is failure of the projections of the upper and lower teeth to interdigitate properly.

Caries and the Role of Bacteria and Ingested Carbohydrates.

It is generally agreed that caries result from the action of bacteria on the teeth, the most common of which is Streptococcus mutans. The first event in the develop-ment of caries is the deposit of plaque, a film of pre-cipitated products of saliva and food, on the teeth. Large numbers of bacteria inhabit this plaque and are readily available to cause caries. These bacteria depend to a great extent on carbohydrates for their food. When carbohydrates are available, their meta-bolic systems are strongly activated and they multiply. In addition, they form acids (particularly lactic acid) and proteolytic enzymes. The acids are the major culprit in causing caries because the calcium salts of teeth are slowly dissolved in a highly acidic medium.

And once the salts have become absorbed, the remain-ing organic matrix is rapidly digested by the prote-olytic enzymes.

The enamel of the tooth is the primary barrier to the development of caries. Enamel is far more resistant to demineralization by acids than is dentin, primarily because the crystals of enamel are dense, but also because each enamel crystal is about 200 times as large in volume as each dentin crystal. Once the carious process has penetrated through the enamel to the dentin, it proceeds many times as rapidly because of the high degree of solubility of the dentin salts.

Because of the dependence of the caries bacteria on carbohydrates for their nutrition, it has frequently been taught that eating a diet high in carbohydrate content will lead to excessive development of caries. However, it is not the quantity of carbohydrate ingested but the frequency with which it is eaten that is important. If carbohydrates are eaten in many small parcels throughout the day, such as in the form of candy, the bacteria are supplied with their preferential metabolic substrate for many hours of the day, and the development of caries is greatly increased.

Role of Fluorine in Preventing Caries. Teeth formed in chil-dren who drink water that contains small amounts of fluorine develop enamel that is more resistant to caries than the enamel in children who drink water that does not contain fluorine. Fluorine does not make the enamel harder than usual, but fluorine ions replace many of the hydroxyl ions in the hydroxyapatite crys-tals, which in turn makes the enamel several times less soluble. Fluorine may also be toxic to the bacteria. Finally, when small pits do develop in the enamel, flu-orine is believed to promote deposition of calcium phosphate to “heal” the enamel surface. Regardless of the precise means by which fluorine protects the teeth, it is known that small amounts of fluorine deposited in enamel make teeth about three times as resistant to caries as teeth without fluorine.

Malocclusion. Malocclusion is usually caused by ahereditary abnormality that causes the teeth of one jaw to grow to abnormal positions. In malocclusion, the teeth do not interdigitate properly and therefore cannot perform their normal grinding or cutting action adequately. Malocclusion occasionally also results in abnormal displacement of the lower jaw in relation to the upper jaw, causing such undesirable effects as pain in the mandibular joint and deterioration of the teeth.

The orthodontist can usually correct malocclusion by applying prolonged gentle pressure against the teeth with appropriate braces. The gentle pressure causes absorption of alveolar jaw bone on the com-pressed side of the tooth and deposition of new bone on the tensional side of the tooth. In this way, the tooth gradually moves to a new position as directed by the applied pressure.

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Medical Physiology: Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth : Dental Abnormalities |

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