Morphoea
Morphoea
is a localized form of scleroderma with pale indurated plaques on the skin but
no internal sclerosis (Figs 10.12 and 10.13). Many plaques are surrounded by a
violaceous halo. Its prognosis is usu-ally good, and the fibrosis slowly clears
leaving slight depression and hyperpigmentation. A rare type may lead to arrest
of growth of the underlying bones caus-ing, for example, facial hemiatrophy or
shortening of a limb. Little is known about the cause, except that Lyme
borreliosis may be associated with the dis-ease in Europe but not in the
Americas. Treatments work slowly, if at all, and include topical steroids,
calcipotriene, non-steroidal anti-inflammatory drugs (NSAIDs), psoralen with
ultraviolet A (PUVA), UVA and hydroxychloroquine in selected patients.
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