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Why do we need vitamins?
Micronutrients (vitamins and minerals) are also listed on food packaging. Thevitamins we require are compounds that are necessary for metabolic processes; either our bodies cannot synthesize them, or they cannot synthesize them in amounts sufficient for our needs. As a result, we must obtain vitamins from dietary sources. DVs are listed for the fat-soluble vitamins—vitamins A, D, and E—but care must be taken to avoid overdoses of these vitamins. Excesses can be toxic when large amounts of fat-soluble vitamins accumulate in adipose tissue. Excess vitamin A is especially toxic. With water-soluble vitamins, turnover is frequent enough that the danger of excess is not normally a problem.
The water-soluble vitamins with listed DVs are vitamin C, which is necessary for the prevention of scurvy, and the B vitamins—niacin, panto-thenic acid, vitamin B6, riboflavin, thiamine, folic acid, biotin, and vitamin B12. The B vitamins are the precursors of the metabolically important coenzymes listed in Table 7.1, where references to the reactions in which the coenzymes play a role are given. We have seen many pathways in which NADH, NADPH, FAD, TPP, biotin, pyridoxal phosphate, and coenzyme A were found, all of which came from vitamins. A summary of vitamins and their metabolic roles is given in Table 24.2. Frequently, the actual biochemical role is played by a metabolite of the vitamin rather than by the vitamin itself, but this point does not affect the dietary requirement.
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