RHINOVIRUS DISEASE
Rhinoviruses are
known as the common cold viruses. They represent the major causes of mild URI
syndromes in all age groups, especially older children and adults. Lower
respiratory tract disease caused by rhinoviruses is uncommon. The usual
incubation period is 2 to 3 days, and acute symptoms commonly last 3 to 7 days.
Interestingly, mucosal cell damage is minimal during the illness. Data suggest
that activation and an increase in kinins, particularly bradykinin, may have a
major role in the pathogenesis of increased secretions, vasodilation, and sore
throat. Rhinovirus infections may be seen at any time of the year. Epidemic
peaks tend to occur in the early fall or spring months.
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