PARAINFLUENZA VIRUSES
VIROLOGY
There are four serotypes of parainfluenza viruses:
parainfluenza 1, 2, 3, and 4. These en-veloped viruses belong to the
paramyxovirus group; contain nonsegmented, negative-sense, single-stranded RNA;
and, like the influenza viruses, possess a neuraminidase and hemag-glutinin.
Their mode of spread and pathogenesis is similar to that of the influenza
viruses. They differ from the influenza viruses in that RNA synthesis occurs in
the cytoplasm rather than the nucleus. In addition, the antigenic makeup of the
four serotypes is relatively stable, and significant antigenic shift or drift
does not occur. Each serotype is considered separately.
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