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Paediatrics: Exanthem 6: human herpes virus 6

Human herpes virus 6 (HHV6) is a benign, self-limiting exanthem com-monly infecting children by the age of 2yrs.

Exanthem 6: human herpes virus 6

 

Human herpes virus 6 (HHV6) is a benign, self-limiting exanthem com-monly infecting children by the age of 2yrs. It is also known as ‘roseola infantum’ and ‘erythema subitum’.

 

Signs and symptoms

 

Prodrome. High-spiking fever up to 41*C lasting for up to 4 days. The fever typically stops once the rash appears.

 

Exanthematous phase: the rose-coloured maculopapular rash appears some days later, beginning on the trunk and spreading peripherally. It lasts for 2–5 days.

 

Other features: vomiting, diarrhoea, pharyngeal injection without exudates, cervical lymphadenopathy, and febrile convulsions prior to rash (5–10% of cases).

 

Diagnosis 

Diagnosis is on clinical grounds. Typical history and there may be associ-ated neutropenia.

 

 

Management 

Management is supportive: antipyretics for fever.

 

Complications

   The most common complication is febrile convulsion, and HHV6 probably accounts for a third of these in those <1yr of age. Rarely, some children may develop aseptic meningitis, encephalitis, and hepatitis.

 

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Paediatrics: Infectious diseases : Paediatrics: Exanthem 6: human herpes virus 6 |


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