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Chapter: Modern Medical Toxicology: Neurotoxic Poisons: Anaesthetics and Muscle Relaxants

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Muscle Relaxants

Four Classification of Muscle Relaxants.

MUSCLE RELAXANTS

·      Central Skeletal Muscle Relaxants—

·              Baclofen, carisoprodol, chlormezanone, chlorzoxazone, metaxalone, methocarbamol, tizanidine.

·      Neuromuscular Blocking Agents—

o     Depolarisers: Succinylcholine, decamethonium.

o     Non-depolarisers:

i.                  Benzylisoquinolines: Atracurium, cis-atracu-rium, doxacurium, metocurine, mivacurium, tubocurarine.

ii.                  Ammoniosteroids: Pancuronium, pipecuronium, rocuronium, vecuronium.

iii.                  Gallamine is a synthetic drug that is no more used today.

·      Miscellaneous Drugs—

Orphenadrine, dantrolene, cyclobenzaprine.


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