Intravenous Anaesthetics
The toxic profile of barbiturates, benzodiazepines, and
opiates has been discussed elsewhere and hence will not be dealt with here.
Etomidate
Etomidate is a synthetic carboxylate imidazole and is a
potent ultra-short acting hypnotic agent without analgesic properties. Overdose
may result in prolonged unconsciousness. Etomidate inhibits adrenal
steroidogenesis which may be the reason for increased mortality when it was
used for prolonged sedation of critically ill patients.
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