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Chapter: Medical Surgical Nursing: Assessment and Management of Patients With Endocrine Disorders

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Management of Patients With Adrenal Disorders

Management of Patients With Adrenal Disorders
There are two adrenal glands in the human, each attached to the upper portion of a kidney. Each adrenal gland is, in reality, two endocrine glands with separate, independent functions.

Management of Patients With Adrenal Disorders

There are two adrenal glands in the human, each attached to the upper portion of a kidney. Each adrenal gland is, in reality, two endocrine glands with separate, independent functions. The adrenal medulla at the center of the gland secretes catechol-amines, and the outer portion of the gland, the adrenal cortex, secretes steroid hormones (Fig. 42-6). The secretion of hormones from the adrenal cortex is regulated by the hypothalamic-pituitary-adrenal axis. The hypothalamus secretes corticotropin-releasing hormone (CRH), which in turn stimulates the pituitary gland to secrete ACTH. ACTH then stimulates the adrenal cor-tex to secrete glucocorticoid hormone (cortisol). Increased levels of the adrenal hormone then inhibit the production or secretion of CRH and ACTH. This system is an example of a negative feedback mechanism.


 

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