1. Colostrum provides
a) Naturally acquired active immunity
b) Naturally acquired passive immunity
c) Artificially acquired active immunity
d) Artificially acquired passive immunity
2. Paratope is an
a) Antibody binding site on variable regions
b) Antibody binding site on heavy regions
c) Antigen binding site on variable regions
d) Antigen binding site on heavy regions
3. Allergy involves
4. Anaphylactic shock is due to
a) Allergic reaction
b) Secretion of toxins
c) Secretion of histamines
d) All the above
5. Spread of cancerous cells to distant sites is termed as
d) Malignant neoplasm
6. AIDS virus has
a) Single stranded RNA
b) Double stranded RNA
c) Single stranded DNA
d) Double stranded DNA
7. All are peripheral lymphoid organs except
a) Lymph nodes
c) Mucosa associated lymphoid tissue
8. Which is not a macrophage?
c) Kupffer cell
9. True about interferon is that
a) It is synthetic antiviral agent
b) It inhibits viral replication in cells
c) It is specific for a particular virus
d) It causes infection
10. Cell mediated immunity is carried out by………….. while humoral immunity is mainly carried out by
a) B cells/T cells
c) T cells/B cells
11. B Cells are activated by
9. In agglutination and precipitation reactions, the antigen is a ______________ and ____________ respectively
a) Whole cell/soluble molecule
b) Soluble molecule/whole cell
13. B cells that produce and release large amounts of antibody are called
a) Memory cells
c) Plasma cells
d) killer cells
14. Raja is injured and got swelling. The swelling is due to the infection of tissue is an example of
a) Mechanical barrier
b) Physiological barrier
15. Given below are some human organs. Identify one primary and one secondary
lymphoid organ. Explain its role.
Liver, thymus, stomach, thyroid, tonsils
16. How does saliva act in body defence?
17. How does immune system work?
18. Name and explain the type of barriers which involve macrophages.
19. What are interferons? Mention their role.
20. List out chemical alarm signals produced during inflammation.
21. Differentiate between
(A) Innate immunity and acquired immunity
(B) Primary and secondary immune responses
(C) Active and passive immunity
(D) Humoral and CMI immunity
(E) Autoimmune disease and Immunodeficiency disease
22. Where are B-cells and T-cells produced in the human body? How do they differ from each other? Mention any two differences.
23. Explain the process of replication of retrovirus after it gains entry into the human body.
24. Why is an antibody molecule represented as H2 L2?
25. Explain the structure of immunoglobulin with suitable diagram.
26. What are the cells involved innate immune system?
27. Why is opsonisation efficient in phagocytosis?
28. What is vaccine? What are its types?
29. A person is infected by HIV. How will you diagnose for AIDS?
30. Autoimmunity is a misdirected immune response. Justify.
Extra One mark Questions and Answers [ ]
1. Select the correct statement from the given below.
a) Barbiturates when given to criminals make them tell the truth
b) Morphine is often given to persons who have under gone surgery as a pain killer
c) Chewing tobacco lowers blood pressure and heart rate
d) Cocaine is given to patients after surgery as it stimulates recovery
2. Match the following
i) Treptonema pallidum
ii) Use only sterilized food and water
iii) DPT vaccine
iv) Use oral rehydration Therapy
a) A:i, B:ii,C: iii, D: iv
b) A:ii, B:iv,C:i, D:iii
c) A:ii, B:i,C:iii, D:iv
d) A:ii, B:iii,C:iv, D:i
3. If a person shows production of interferons in his body, the chances are that he has got an infection of
4. A person suffering from a disease caused by Plasmodium, experiences recurring chill and fever at the time when?
a) The sporozoites released from RBC’s are being rapidly killed and broken down inside spleen
b) The trophozoites reach maximum growth and give out certain toxins.
c) The parasite after its rapid multiplication inside RBC’s reptures them, releasing the stage to enter fresh RBC’s
d) The microgametocytes and megagametocytes are being destroyed by the WBC’s
5. Where will you look for the sporozoites of the material parasite?
a) Red blood corpuscles of humans suffering from malaria.
b) Spleen of infected humans
c) Salivary glands of freshy moulted female anopheles mosquito.
d) Saliva of infected female anopheles mosquito.
6. Which one of the following organisms is scientifically and correctly named, correctly printed according to the International Rules of Nomenclature and correctly described?
a) Plasmodium falciparum – a protozoan causing the most serious type of malaria.
b) Felis tigris – The Indian tiger is well protected in Gir forests.
c) E. Coli – The full name is Entamoeba coli, a commonly occurring bacterium in human intestine.
7. Which of the following endoparasites of humans does show vivipaity?
a) Ancylostoma duodenale
b) Enterobius vermicularis
c) Trichimella spiralis
d) Ascaris lumbricoides
8. The active form of Entamoeba histolytica feeds upon:
a) Erythrocytes, mucosa and submucosa of colon
b) Mucosa and submucosa colon only
c) Food in intestine
d) Blood only
9. Which one of the following statements is correct with respect to AIDS?
a) The HIV can be transmitted through eating food together with an infected person.
b) Drug addicts are least susceptible to HIV infection.
c) AIDS patients are being fully cured 100 percent with proper care and nutrition.
d) The causative HIV retrovirus enters helper T-lymphocytes thus reducing their numbers.
10. Select the correct statement with respect to diseases and immunization
a) If due to some reason B and T lymphocytes are damaged, the body will not produce antibodies against a pathogen
b)Injection of dead/inactivated pathogens caused passive immunity
c) Certain protozoans have been used in mass production of hepatitis B vaccine.
d) Injection of snake antivenom against snake bite is an example of active immunization.
11. Which one of the following statements is correct with respect to immunity?
a) The antibodies against small pox pathogen are produced by T – lymphocytes
b) Antibodies are protein molecules each of which has four light chains.
c) Rejection of a kidney graft is the function of B – lymphocytes.
d) Preformed antibodies need to be injected to treat the bite by a viper snake.
12. Which one of the following is not a property of cancerous cells whereas the remaining three are?
a) They compete with normal cells for vital nutrients
b) They do not remain confined in the area of formation
c) They divide in an uncontrolled manner
d) They show contact inhibition
13. At which stager HIV infection does one usually show
symptoms of AIDS?
a) Within 15 days of sexual contact with an infected person
b) When the infected retro virus enters host cells
c) When HIV damages large number of helper T-Lymphocytes
d) When the viral DNA is produced by reverse transcriptase
14. Match each disease with its correct type of vaccine
a)Tuberculosis i) harmless virus
b)Whooping cough ii) inactivated toxin
c)Diphtheria iii) killed bacteria
d)Polio iv) harmless bacteria
a) a-(ii) b-(i) c-(iii) d-(iv)
b) a-(iii) b-(ii) c-(iv) d-(i)
c) a-(iv) b-(iii) c-(ii) d-(i)
d) a-(i) b-(ii) c-(iv) d-(iii)
15. Which of the following is correct regarding AIDS causative agent HIV?
a) HIV is enveloped virus that contains two identical molecules of single-stranded RNA and two molecules of reverse transcriptase
b) HIV is unenveloped retrovirus
c) HIV does not escape but attacks the acquired immune response
d) HIV is enveloped virus containing one molecule of single – stranded RNA and one molecule of reverse transcriptase