DNA replication in eucaryotes

DNA replication in eucaryotes

In eucaryotic organisms, the DNA is linear, not circular, so the process of replication differs in some respects. Genome sizes are generally much bigger in eucaryotes, and replication much slower, so numerous replication forks are active simultaneously on each chromosome. Replication takes place bidirectionally, creating numerous replica-tion bubbles (Figure 11.4) which merge with one another until the whole chromosome has been covered.