Chapter: Microbiology and Immunology: Bacteriology: Campylobacter and Helicobacter

Treatment, Prevention and Control of Helicobacter pylori Infections

H. pylori is sensitive to several antibiotics and to bismuth salts.

Treatment

H. pylori is sensitive to several antibiotics and to bismuth salts. Use of a single antibiotic or an antibiotic contained with bis-muth is not effective. More success has been achieved for treatment of gastric or peptic ulcer by using a combination of bismuth, a proton pump inhibitor (e.g., omeprazole), and one or more antibiotics (ampicillin, metronidazole, clarithromycin, tetracycline). The combination of three types of drug is known as triple therapy and is usually given for either 10 or 14 days.

Recently, H. pylori strains resistant to macrolides have been reported. Also, some strains resistant to clarithromycin have been documented in children.

Prevention and Control

Improved personal hygiene is important in prevention of the disease.

Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail

Microbiology and Immunology: Bacteriology: Campylobacter and Helicobacter : Treatment, Prevention and Control of Helicobacter pylori Infections |