A combination therapy of pegylated interferon and antiviral agent ribavirin is the current option of treatment for patients with chronic HCV infections. Other therapeutic options include the use of protease inhibitors, ribozymes, and viral vaccines.
Prevention and Control
No vaccine against HCV is available. Immunoglobulin is not useful in preventing transmission and, in fact, administration of immunoglobulin has been associated with HCV. Trans-mission of HCV can be prevented by screening and preventing donation of blood, organs, or semen from HCV-positive donors. Differentiating features of HAV, HBV, and HCV are summarized in Table 66-4.