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Chapter: Microbiology and Immunology: Virology, Virus: Arboviruses

Treatment, Prevention and Control - Hepatitis A Virus Infections

No antiviral therapy is available against HAV infection. Treatment of the condition is always supportive.

Treatment

No antiviral therapy is available against HAV infection. Treatment of the condition is always supportive.

Prevention and Control

Prevention of HAV infection depends on: (a) vaccines, (b) prophylaxis with immune serum globulin, and (c) measures to prevent feco-oral spread of infection.

 Immunoglobulin

Postexposure prophylaxis consists of administration of hepati-tis A immunoglobulin to contacts within 2 weeks of exposure. The immunoglobulin is given in a dose of 0.02 mL administered intramuscularly in a single dose. Postexposure prophylaxis is recommended for household contact of infected patients and contact in child-care center during outbreaks.

 Prevention of fecal–oral spread of infection

General prevention measures consist of hand washing, drinking of safe drinking water, and good personal hygiene and sanita-tion. All these contribute to prevention of fecal–oral spread of infection of HAV.


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Microbiology and Immunology: Virology, Virus: Arboviruses : Treatment, Prevention and Control - Hepatitis A Virus Infections |


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