No antiviral therapy is available against HAV infection. Treatment of the condition is always supportive.
Prevention of HAV infection depends on: (a) vaccines, (b) prophylaxis with immune serum globulin, and (c) measures to prevent feco-oral spread of infection.
Postexposure prophylaxis consists of administration of hepati-tis A immunoglobulin to contacts within 2 weeks of exposure. The immunoglobulin is given in a dose of 0.02 mL administered intramuscularly in a single dose. Postexposure prophylaxis is recommended for household contact of infected patients and contact in child-care center during outbreaks.
General prevention measures consist of hand washing, drinking of safe drinking water, and good personal hygiene and sanita-tion. All these contribute to prevention of fecal–oral spread of infection of HAV.
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