Although imaging techniques such as PET and SPECT have helped bring about tremendous advances in the study of brain diseases, they have some limitations:
· The use of radioactive substances in PET and SPECT limits the number of times a person can undergo these tests. There is the risk that the client will have an aller-gic reaction to the substances. Some clients may find receiving intravenous doses of radioactive material frightening or unacceptable.
· Imaging equipment is expensive to purchase and maintain, so availability can be limited. A PET camera costs about $2.5 million; a SPECT camera costs about $500,000.
· Some persons cannot tolerate these procedures because of fear or claustrophobia.
· Researchers are finding that many of the changes in dis-orders such as schizophrenia are at the molecular and chemical levels and cannot be detected with current imaging techniques (Fujita et al., 2005; Vythilingam et al., 2005).
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