CULTURAL CONSIDERATIONS
Studies have shown that people from different ethnic back-grounds
respond differently to certain drugs used to treat mental disorders. The nurse
should be familiar with these cultural differences. Studies have also shown
that African Americans respond more rapidly to antipsychotic medica-tions and
tricyclic antidepressants than do whites. Also, African Americans have a
greater risk for developing side effects from both these classes of drugs than
do whites. Asians metabolize antipsychotics and tricyclic antidepres-sants more
slowly than do whites and therefore require lower dosages to achieve the same
effects. Hispanics also require lower dosages of antidepressants than do whites
to achieve the desired results (Woods et al., 2003).
Asians respond therapeutically to lower dosages of lith-ium than do
whites. African Americans have higher bloodlevels of lithium than whites when
given the same dosage, and they also experience more side effects. This
suggests that African Americans require lower dosages of lithium than do whites
to produce desired effects (Chen et al., 2002).
Herbal medicines have been used for hundreds of years in many
countries and are now being used with increasing frequency in the United
States. St. John’s wort is used to treat depression and is the second most
commonly pur-chased herbal product in the United States (Malaty, 2005). Kava is
used to treat anxiety and can potentiate the effects of alcohol, benzodiazepines,
and other sedative–hypnotic agents. Valerian helps produce sleep and is
sometimes used to relieve stress and anxiety. Ginkgo biloba is primar-ily used
to improve memory but is also taken for fatigue, anxiety, and depression.
It is essential for the nurse to ask clients specifically if they
use any herbal preparations. Clients may not consider these products as
“medicine” or may be reluctant to admit their use for fear of censure by health
professionals. Herbal medicines are often chemically complex and are not
stan-dardized or regulated for use in treating illnesses. Combin-ing herbal
preparations with other medicines can lead to unwanted interactions, so it is
essential to assess the clients’ use of these products.
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