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Chapter: Basic & Clinical Pharmacology : Thyroid &Antithyroid Drugs

Antithyroid Agents

Reduction of thyroid activity and hormone effects can be accom-plished by agents that interfere with the production of thyroid hormones.

ANTITHYROID AGENTS

Reduction of thyroid activity and hormone effects can be accom-plished by agents that interfere with the production of thyroid hormones, by agents that modify the tissue response to thyroid hormones, or by glandular destruction with radiation or surgery. Goitrogens are agents that suppress secretion of T3 and T4 to sub-normal levels and thereby increase TSH, which in turn produces glandular enlargement (goiter). The antithyroid compounds used clinically include the thioamides, iodides, and radioactive iodine.

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Basic & Clinical Pharmacology : Thyroid &Antithyroid Drugs : Antithyroid Agents |


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