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Chapter: Biotechnology: Genomics and Bioinformatics

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Analysis using Bioinformatics tools

Many kinds of analysis can be made using various bioinformatics tools.

Analysis using Bioinformatics tools

 

Many kinds of analysis can be made using various bioinformatics tools. These include:

 

Processing raw information: The experimentally determined sequence (raw information) is processed using bioinformatics tools into genes, the proteins encoded and their function, the regulatory sequences, and inferring phylogenetic relationships.

 

Genes: Gene prediction can be done by using computer programs like GeneMark for bacterial genomes and GENSCAN for eukaryotes.

 

Proteins: Protein sequences can be inferred from the predicted genes by using simple computer programs.


Regulatory sequences: Regulatory sequences can also be identified and analysed by using bioinformatics tools.


Inferring phylogenetic relationships: Information regarding the relationships between organisms can be obtained by aligning multiple sequences, calculating evolutionary distance and constructing phylogenetic trees.


Making a Discovery: Using the bioinformatics tools and databases, the functions of unknown genes can be predicted.

 

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