Metal Fume Fever
Brass
chills; Brass founder’s ague; Brazier disease; Copper colic; Foundry fever;
Galvanised shakes; “Galvo”; Metal ague; Metal shakes; Monday fever; The shakes;
The smothers; Smelter shakes; Welder’s ague; Zinc chills.
Welding,
galvanising, smelting, metal refining, electroplating, metal polishing,
metallic pigment manufacture, alloy making, ship breaking, etc.
The
syndrome is caused by inhalation of fumes produced when the following metals
are heated above their melting point (indecreasing
order of importance): zinc, copper, magnesium,iron, chromium, cadmium,
nickel, manganese, mercury, cobalt, lead, antimony, selenium, beryllium,
vanadium, silver, and aluminium.
·
The syndrome resembles a flu-like
illness, beginning 4 to 6 hours after exposure to fumes, and is characterised
by chills, fever, myalgia, cough, dyspnoea, fatigue, metallic taste,
salivation, thirst, sweating, tachycardia, tachypnoea, leukocytosis, cyanosis,
and reduced pulmonary function tests. The chest x-ray may be clear.
·
Resolution of symptoms occurs 36
hours after stoppage of exposure, so that over the weekend usually the worker
becomes allright only to succumb once again the following Monday (Monday fever).
·
Sequelae are uncommon. Pulmonary
lesions and residual effects are extremely rare and are not generally
considered classical signs of metal fume fever. However, exposure to chromium
and nickel fumes has resulted in increased inci-dence of lung cancer.
Heavy
metal screens or specific metal assay may be necessary to identify a causal
agent in patients with significant acute or chronic toxicity.
·
Symptomatic and non-specific.
Chelation therapy may be required.
·
Corticosteroids have occasionally
been recommended to reduce inflammatory response in patients with serious
pulmonary involvement. Recommended regimen: 60 mg of prednisone per day, which
is then tapered over the next week, or single dose of methylprednisolone 250 to
500 mg IV. Controlled studies demonstrating the benefits of corticosteroids
have not been performed.
·
Analgesics and antipyretics should
be administered as necessary.
·
Prophylactic antibiotics are not
generally recommended unless bacterial infection is suspected.
·
Specific antidotal therapy may be
indicated for symptomatic toxic metal inhalation.
■■ Implementation
of engineering controls.
■■ General
room ventilation.
■■ Local
exhaust ventilation.
■■ Process
enclosure.
■■ Down-draft
or cross-draft tables.
■■ Use
of fume extractors.
A
condition very closely resembling metal
fume fever called polymer fume fever results
from inhalation of gases producedby burning of polytetrafluoroethylene
(Teflon). It is similar in presentation to metal fume fever, with short-term,
flu-like symptoms of sore throat, fever, shivering, and weakness. Symptoms are
usually less severe than with metal fume fever and require only symptomatic
treatment.
Related Topics
Privacy Policy, Terms and Conditions, DMCA Policy and Compliant
Copyright © 2018-2024 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.