Antiviral drugs are available for treatment of VZV infections. These are acyclovir, famciclovir, and valacyclovir. Treatment with these agents is usually recommended for adults and immunocompromised patients with varicella infection and for patients with herpes zoster infections. Antiviral therapy is usu-ally not indicated for treatment of varicella infection in children.
Prevention of transmission of varicella infection in children is difficult.
Varicella zoster immunoglobulin is prepared by pooling sera from patients convalescing from herpes zoster. High-risk peo-ple, such as immunosuppressed patients, are protected from serious disease by administration of varicella zoster immuno-globulin (VZIg). The immunoglobulin is also used for treat-ment of medical and paramedical personnel exposed to virus, as well as for treatment of newborns of infected mothers showing symptoms within 5 days of delivery. It is, however, not useful as a therapy for treatment of patients suffering from active vari-cella or herpes zoster disease.