No specific treatment is available against acute infectious mononucleosis. Acyclovir has little activity against EBV; it may be useful in high doses for treatment of life-threatening EBV infections. Treatment of the condition is mainly symptomatic.
Prevention and Control
Prevention and control of infection is difficult due to wide-spread prevalence of the virus and intermittent shedding of the virus by the infected individuals throughout the life. Avoidance of contact with saliva and avoidance of kissing children on the mouth are some of the preventive measures. No vaccine is available against EBV infection.