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Chapter: Basic & Clinical Pharmacology : Dermatologic Pharmacology

Topical Antiviral Agents

ACYCLOVIR, VALACYCLOVIR, PENCICLOVIR, & FAMCICLOVIR

TOPICAL ANTIVIRAL AGENTS

ACYCLOVIR, VALACYCLOVIR, PENCICLOVIR, & FAMCICLOVIR

Acyclovir, valacyclovir, penciclovir, and famciclovir are synthetic guanine analogs with inhibitory activity against members of the herpesvirus family, including herpes simplex types 1 and 2. Topical acyclovir (Zovirax) is available as a 5% ointment; topical penciclovir (Denavir), as a 1% cream for the treatment of recurrentorolabial herpes simplex virus infection in immunocompetent adults. Adverse local reactions to acyclovir and penciclovir may include pruritus and mild pain with transient stinging or burning.


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Basic & Clinical Pharmacology : Dermatologic Pharmacology : Topical Antiviral Agents |


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