Paediatrics: Mineralocorticoid deficiency

Mineralocorticoid deficiency

Reduced aldosterone production or activity is rare and may be due to congenital or acquired causes.

·Aldosterone synthase deficiency:

·  type 1;

·  type 2.

·Pseudohypoaldosteronism:

·  type 1;

·  type 2.

·Hyporeninaemic hypoaldosteronism.

·Hyperreninaemic hypoaldosteronism.

·Transient hypoaldosteronism in infancy.

·Congenital adrenal hyperplasia:

·  17α-hydroxylase (CYP17) deficiency;

·  11β-hydroxylase (CYP11) deficiency.

·Congenital adrenal hypoplasia.

·Primary adrenocortical insufficiency.

·Latrogenic hypoaldosteronism.