Home | | Paediatrics | Paediatrics: Chronic inflammatory disorders

Chapter: Paediatrics: Growth and puberty

Paediatrics: Chronic inflammatory disorders

Poor growth and short stature is a common feature of long-term inflam-matory conditions such as inflammatory bowel disease and rheumatic dis-orders.

Chronic inflammatory disorders

 

Poor growth and short stature is a common feature of long-term inflam-matory conditions such as inflammatory bowel disease and rheumatic dis-orders. It may be a presenting feature in Crohn’s disease when GI symp-toms are initially minimal.

 

Short stature is due to long-term use of immunosuppressive agents (e.g.

corticosteroids) and to the generation of inflammatory factors (e.g. IL-6).

Both lead to GH/IGF-I resistance and suppression of bone growth.

Management should be aimed at minimizing infl ammation, and reducing immunosuppressive therapy. rhGH may have a role in treatment.

 

Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail
Paediatrics: Growth and puberty : Paediatrics: Chronic inflammatory disorders |


Privacy Policy, Terms and Conditions, DMCA Policy and Compliant

Copyright © 2018-2023 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.