Micturition
The process of release of urine from the bladder is
called micturition or urination. Urine formed by the nephrons is ultimately
carried to the urinary bladder where it is stored till it receives a voluntary
signal from the central nervous system. The stretch receptors present in the
urinary bladder are stimulated when it gets filled with urine. Stretching of
the urinary bladder stimulates the CNS via the sensory neurons of the
parasympathetic nervous system and brings about contraction of the bladder. Simultaneously,
somatic motor neurons induce the sphincters to close. Smooth muscles contracts
resulting in the opening of the internal sphincters passively and relaxing the
external sphincter. When the stimulatory and inhibitory controls exceed the
threshold, the sphincter opens and the urine is expelled out.
An adult human on an average excretes 1 to 1.5 L of
urine per day. The urine formed is a yellow coloured watery fluid which is
slightly acidic in nature (pH 6.0), Changes in diet may cause pH to vary
between 4.5 to 8.0 and has a characteristic odour. The yellow colour of the
urine is due to the presence of a pigment, urochrome. On an average, 25- 30 gms
of urea is excreted per day. Various metabolic disorders can affect the
composition of urine. Analysis of urine helps in clinical diagnosis of various
metabolic disorders and the malfunctioning of the kidneys. For example the
presence of glucose (glucosuria) and ketone bodies (ketonuria) in the urine are
indications of diabetes mellitus.
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