Hands
·
Nails:
o Takes ~ 6 months for fingernails to grow out
o Clubbing:
§ Respiratory: carcinoma, fibrosis, cystic fibrosis, TB, chronic
suppuration (eg bronchiectasis), idiopathic pulmonary fibrosis, NOT asthma or
CORD alone
§ Cardiovascular: infective endocarditis
§ Other (uncommon): cirrhosis, IBD, coeliac disease, thyrotoxicosis
o Blue: cyanosis, Wilson‟s disease
o Red: Polycythaemia (red-blue), carbon monoxide poisoning (cherry red)
o Pale nail bed: anaemia
o Koilonychia: spoon shaped nails in Fe deficiency
o Leuconychia: white nails in hypoalbuminaemia
o Mee‟s lines: single white transverse line in renal failure
o Splinter haemorrhages: usually trauma (especially manual workers) or
infective endocarditis, rarely vasulitis (eg in rheumatoid arthritis),
polyarteritis nodosa, sepsis, blood malignancy or profound anaemia
o Check capillary refill: squeeze nail and see how long it takes to return
to red – sign of peripheral circulation. Normal < 2 sec
·
Hands:
o Palmar erythema: pink spots on pale background – should be bilateral -
Chronic liver disease, pregnancy, rheumatoid arthritis, polycythaemia,
thyrotoxicosis, SLE
o Skin: subcutaneous bleeding: petechiae small, purpura bigger, ecymosis –
biggest. Petechiae caused by a platelet problem, not due to coagulopathy
o Dupuytren‟s Contracture: extend fingers back – shortening of palmar
aponneurosis – in alcoholic liver disease, epilepsy, manual workers and
idiopathic
o Asterixis: metabolic flap – coarse, non-symmetrical – neural inhibition ®
encephalopathy in renal failure (urea), respiratory failure (CO2),
liver failure (nitrogenous material), hypoglycaemia, barbiturate poisoning
o Raynaud‟s Syndrome: intermittent attacks of ischaemia of fingers or toes
due to intense arterial vasospasm, often precipitated by cold or emotional
stimuli
o Tendon Xanthomata: lipid deposits in tendons of hands or arms in
hyperlipidaemia
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