Etiology and Pathophysiology
Currently, the precise etiology and pathogenesis of
ASDs are unknown. Strong evidence for genetic bases for the disorders, along
with the advent of sophisticated genetic techniques, has led to a shift toward looking
for the genetic underpinnings in the disorder. Most contemporary etiological
theories strongly sug-gest a genetic or other early neurodevelopmental
disruption with overt clinical manifestations potentially modified by social or
environmental experiences.
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