Prominent areas of salmon-colored conjunctival thickening frequently occur-ring in the inferior fornix (Fig. 4.25) are often the first sign of lymphatic dis-ease. Identifying the specific forms and degree of malignancy requires biopsy and histologic examination. Lesions may range from benign lymphoid hyper-plasia to malignant lymphomas that are moderately to highly malignant. Because lymphomas respond to radiation, a combination of radiation therapy and chemotherapy is usually prescribed according to the specific histologic findings.