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All Salmonella spp. can cause bacteremia. However, S. Choleraesuis, S. Paratyphi, and S. Typhi more commonly cause a bacteremic disease. Pediatric and geriatric patients as well as patients with AIDS are increasingly susceptible to suffer from Salmonella bacteremia.
The clinical presentations of Salmonella bacteremia are like that of other Gram-negative bacteremias. However, localized suppurative infections, such as osteomyelitis, deep abscesses, endocarditis, arthritis, and meningitis can occur in as many as 10% of patients. The case fatality may be as high as 25%.
Diagnosis of the condition is made by isolation of salmonel-lae from the blood or from the pus from the suppurative lesion and rarely from feces.
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