V. cholerae serotypes from O2 to O139 are known as noncholeravibrios, nonagglutinable vibrios, or V. cholerae non-O1 vibrios. They are similar to V. cholerae O1 biochemically and geneti-cally. V. cholerae O139 is only example of noncholera vibrios that causes cholera as mentioned earlier. Noncholera vibrios other than V. cholerae O139 are widely found in the aquatic environments. In humans, they may cause mild to severe diar-rheal disease resembling cholera. Occasionally, they may also cause wound infections, septicemia, and other extraintestinal infections.