Mycetoma
Mycetoma is a clinical term for an infection
associated with trauma to the foot which causes inoculation of any of a dozen
fungal species. Actinomycetes such as Nocardia
may produce a similar disease. The usual clinical appearance is of massive
induration with draining sinuses. Some of the fungi that cause mycetoma are
geographically wide-spread; most cases, however, occur in the tropics, probably
because the chronically damp, macerated skin of the feet that causes
predisposition toward mycetoma occurs most often among those who go barefoot in
the tropical environment. This finding is illustrated by the case of a college
rower in Seattle who developed mycetoma; he was the only member of his shell
who insisted on rowing barefoot. Once established, the treatment of myce-toma
is difficult. No antimicrobic stands out as particularly helpful. The precise
microbio-logic features depend on the agent involved. Hyphae are usually
present in tissue but may be difficult to demonstrate because of a tendency to
form microcolonial granules.
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