GONORRHEA
N. gonorrhoeae is a gram-negative bacterium that is transmittedprimarily
through sexual contact. Infection can also occur in neonates as a result of
contact during birth. N. gonorrhoeae
can cause mucosal, local, or disseminated infection. Asymptomatic infection is
somewhat common.
Gonorrhea most
frequently manifests with local manifestations. In men, urethritis and
epididymitis are the most common symp-toms. Gonorrhea is more likely to be
asymptomatic in women than in men. The uterine cervix is the primary site of
local infec-tion, and symptoms often include urinary tract infection, increased
vaginal discharge, and itching. The most common complication of localized
gonococcal infection in women is pelvic inflamma-tory disease (PID), in which
the organism infects the uterus, fal-lopian tubes, or peritoneal fluid. A
complication of gonococcal PID is increased risk for ectopic pregnancy and
bilateral tubal occlusion, which results in infertility.
In rare circumstances, the organism may disseminate in
un-treated, infected people. Other systemic signs, such as arthritis or
dermatitis, can accompany bacteremia. In rare instances, valves of the heart
can be infected with N. gonorrhoeae,
or gonococcal meningitis can develop.
The patient is assessed for fever; for urethral, vaginal, and rectal discharge; and for signs of arthritis. Culture and sensitivity stud-ies are the usual and preferred methods of diagnosing and verify-ing effectiveness of therapy. In the male patient, specimens are obtained from the urethra, anal canal, and pharynx. In the female patient, cultures are obtained from the endocervix, pharynx, and anal canal.
When obtaining these cultures, the nurse should wear
disposable gloves and wash hands thoroughly after glove re-moval. Lubricating
jelly is not used for the vaginal examination because it may contain substances
that inhibit growth or kill some pathogens, decreasing the microbiologic test
accuracy. In-stead, water is used as the lubricant. Because N. gonorrhoeae or-ganisms are
susceptible to environmental changes, specimens must be delivered to the
laboratory immediately after they are obtained.
The CDC-recommended
treatment for gonorrheal infections is administration of ceftriaxone (Rocephin)
(or cefixime [Suprax], ciprofloxacin [Cipro], or ofloxacin [Floxin]) along with
doxy-cycline. Doxycycline is added to first-line therapy to treat presumptive Chlamydia trachomatis, which commonly
causes co-infection in patients with gonorrhea. Patients with uncomplicated
gonorrhea who are treated with CDC-recommended therapy do not routinely need to
return for a proof-of-cure visit. If the pa-tient reports a new episode of
symptoms or tests reveal gonorrhea again, the most likely explanation is
reinfection rather than treat-ment failure. Serologic testing for syphilis and
HIV should be offered to patients with gonorrhea, because any STD increases the
risk for other STD infections.
Gonorrhea is a reportable communicable disease. In any
health care facility, a mechanism should be in place to ensure that all
pa-tients diagnosed with gonorrhea are reported to the local public health
department to ensure follow-up of the patient. The pub-lic health department
also is responsible for interviewing the pa-tient to identify sexual contacts,
so that contact notification and screening can be initiated.
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