Endometrial
Carcinoma
Approximately 2% to 3% of women
will develop uterine cancer during their lifetime. Ninety-sevenpercent of all
uterine cancers arise from the glands of the endometrium and are known as endometrial carcinomas. The
remaining 3% of uterine cancers arise frommesenchymal uterine components and
are classified as sarcomas.
Endometrial
carcinoma is the most common genital tract malignancy and the fourth most
common cancer after breast, bowel, and lung carcinoma. Approximately
39,000 new casesof endometrial carcinoma were diagnosed in 2007, result-ing in
over 7400 deaths. Fortunately, patients with this disease usually present early
in the disease course with some form of abnormal uterine bleeding (AUB),
particularly postmenopausal bleeding. With early diagnosis, survival rates are
excellent.
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